Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis

The siRNA silencing approach has long been used as a method to regulate the expression of specific target genes in vitro and in vivo. However, the effectiveness of delivery and the nonspecific immune-stimulatory function of siRNA are the limiting factors for therapeutic applications of siRNAs. To ov...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yoon, Pyoung Oh, Park, Jin Wook, Lee, Chang-Min, Kim, Sung Hwan, Kim, Han-Na, Ko, Youngho, Bae, Seon Joo, Yun, Sungil, Park, Jun Hong, Kwon, Taewoo, Kim, Woo Seok, Lee, Jiyoung, Lu, Qing, Kang, Hye-Ryun, Cho, Won-Kyung, Elias, Jack A., Yang, Joo-Sung, Park, Han-Oh, Lee, Kyuhong, Lee, Chun Geun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813554/
https://ncbi.nlm.nih.gov/pubmed/26817844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693671
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