Safety pharmacology of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle platform

The present safety pharmacology core battery studies (neurobehavior, respiratory, cardiovascular system, and human ether a-go-go (hERG) channel current) investigated the potential harmful effects of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG). The SAMiRNA-AREG was adm...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Kim, Tae Rim, Kim, Hyeon-Young, Kim, In-Hyeon, Kim, Ki Cheon, Ko, Youngho, Park, Jun Hong, Yun, Sungil, Lee, In-Chul, Kim, Sung-Hwan, Park, Han-Oh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065257/
https://ncbi.nlm.nih.gov/pubmed/33912399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2021.03.022
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