Efficacy of Antimicrobial Peptide DP7, Designed by Machine-Learning Method, Against Methicillin-Resistant Staphylococcus aureus

Antimicrobial peptides (AMPs) provide a promising strategy against infections involving multidrug-resistant pathogens. In previous studies, we designed a short 12 amino acid AMP DP7, using a machine-learning method based on an amino acid activity contribution matrix. DP7 shows broad-spectrum antimic...

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Vydáno v:Front Microbiol
Hlavní autoři: Zhang, Rui, Wang, Zhenling, Tian, Yaomei, Yin, Qi, Cheng, Xingjun, Lian, Mao, Zhou, Bailing, Zhang, Xueyan, Yang, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546875/
https://ncbi.nlm.nih.gov/pubmed/31191493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01175
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