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Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum

A fast and easy-to-use liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination and quantification of a novel antifungal drug, olorofim (F901318), a member of the novel class of orotomides, in human plasma and serum was developed and validated. Sample preparation was ba...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Müller, Carsten, Fietz, Cornelia, Koehler, Philipp, Sibley, Graham, Nforbugwe, Achu Che Awah, Streichert, Thomas, Wiesen, Martin H. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201104/
https://ncbi.nlm.nih.gov/pubmed/30150474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01356-18
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