Mechanism of Macrolide-Induced Inhibition of Pneumolysin Release Involves Impairment of Autolysin Release in Macrolide-Resistant Streptococcus pneumoniae

Streptococcus pneumoniae is a leading cause of community-acquired pneumonia. Over the past 2 decades, macrolide resistance among S. pneumoniae organisms has been increasing steadily and has escalated at an alarming rate worldwide. However, the use of macrolides in the treatment of community-acquired...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Domon, Hisanori, Maekawa, Tomoki, Yonezawa, Daisuke, Nagai, Kosuke, Oda, Masataka, Yanagihara, Katsunori, Terao, Yutaka
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201085/
https://ncbi.nlm.nih.gov/pubmed/30181369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00161-18
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