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Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis

Streptococcus pneumoniae is a leading cause of bacterial pneumonia and is the principal cause of morbidity and mortality worldwide. Previous studies suggested that excessive activation of neutrophils results in the release of neutrophil elastase, which contributes to lung injury in severe pneumonia....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Domon, Hisanori, Oda, Masataka, Maekawa, Tomoki, Nagai, Kosuke, Takeda, Wataru, Terao, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125098/
https://ncbi.nlm.nih.gov/pubmed/27892542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38013
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