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Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis

Streptococcus pneumoniae is a leading cause of bacterial pneumonia and is the principal cause of morbidity and mortality worldwide. Previous studies suggested that excessive activation of neutrophils results in the release of neutrophil elastase, which contributes to lung injury in severe pneumonia....

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Domon, Hisanori, Oda, Masataka, Maekawa, Tomoki, Nagai, Kosuke, Takeda, Wataru, Terao, Yutaka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125098/
https://ncbi.nlm.nih.gov/pubmed/27892542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38013
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