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Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays

Intrinsically disordered regions (IDRs) are protein regions that lack persistent secondary or tertiary structure under native conditions. IDRs represent >40% of the eukaryotic proteome and play a crucial role in protein–protein interactions. The classical approach for identification of these inte...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Harnoš, Jakub, Ryneš, Jan, Víšková, Pavlína, Foldynová-Trantírková, Silvie, Bajard-Ešner, Lola, Trantírek, Lukáš, Bryja, Vítězslav
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200943/
https://ncbi.nlm.nih.gov/pubmed/30166345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005127
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