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Multi-tiered pairing selectivity between E2 ubiquitin–conjugating enzymes and E3 ligases

Ubiquitination is a prevalent post-translational modification involved in all aspects of cell physiology. It is mediated by an enzymatic cascade and the E2 ubiquitin–conjugating enzymes (UBCs) lie at its heart. Even though E3 ubiquitin ligases determine the specificity of the reaction, E2s catalyze...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Turek, Ilona, Tischer, Nadine, Lassig, Roman, Trujillo, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200922/
https://ncbi.nlm.nih.gov/pubmed/30185618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004226
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