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Efficient biosynthesis of heterodimeric C(3)-aryl pyrroloindoline alkaloids

Many natural products contain the hexahydropyrrolo[2, 3-b]indole (HPI) framework. HPI containing chemicals exhibit various biological activities and distinguishable structural arrangement. This structural complexity renders chemical synthesis very challenging. Here, through investigating the biosynt...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tian, Wenya, Sun, Chenghai, Zheng, Mei, Harmer, Jeffrey R., Yu, Mingjia, Zhang, Yanan, Peng, Haidong, Zhu, Dongqing, Deng, Zixin, Chen, Shi-Lu, Mobli, Mehdi, Jia, Xinying, Qu, Xudong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200733/
https://ncbi.nlm.nih.gov/pubmed/30356123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06528-z
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