STAT6 and Furin Are Successive Triggers for the Production of TGFβ by T Cells

Production of transforming growth factor-β (TGFβ) by T cells is key to various aspects of immune homeostasis, with defects in this process causing or aggravating immune-mediated disorders. The molecular mechanisms that lead to TGFβ generation by T cells remain largely unknown. To address this issue,...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Li, Yue, Liu, Weiren, Guan, Xiaqun, Truscott, Jamie, Creemers, John W., Chen, Hung-Lin, Pesu, Marko, El Abiad, Rami G., Karacay, Bahri, Urban, Joseph F., Elliott, David E., Kaplan, Mark H., Blazar, Bruce R., Ince, M. Nedim
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200631/
https://ncbi.nlm.nih.gov/pubmed/30266770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700808
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