Inherited Genetic Variants Associated with Melanoma BRAF/NRAS Subtypes

BRAF and NRAS mutations arise early in melanoma development but their associations with low-penetrance melanoma susceptibility loci remain unknown. In the Genes, Environment and Melanoma (GEM) Study, 1223 European-origin participants had their incident invasive primary melanomas screened for BRAF/NR...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Thomas, Nancy E., Edmiston, Sharon N., Orlow, Irene, Kanetsky, Peter A., Luo, Li, Gibbs, David C., Parrish, Eloise A., Hao, Honglin, Busam, Klaus J., Armstrong, Bruce K., Kricker, Anne, Cust, Anne E., Anton-Culver, Hoda, Gruber, Stephen B., Gallagher, Richard P., Zanetti, Roberto, Rosso, Stefano, Sacchetto, Lidia, Dwyer, Terence, Ollila, David W., Begg, Colin B., Berwick, Marianne, Conway, Kathleen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200630/
https://ncbi.nlm.nih.gov/pubmed/29753029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.04.025
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