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Association Between NRAS and BRAF Mutational Status and Melanoma-Specific Survival Among Patients With Higher Risk Primary Melanoma

IMPORTANCE: NRAS and BRAF mutations in melanoma inform current treatment paradigms but their role in survival from primary melanoma has not been established. Identification of patients at high risk of melanoma-related death based on their primary melanoma characteristics before evidence of recurrenc...

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Pubblicato in:JAMA Oncol
Autori principali: Thomas, Nancy E., Edmiston, Sharon N., Alexander, Audrey, Groben, Pamela A., Parrish, Eloise, Kricker, Anne, Armstrong, Bruce K., Anton-Culver, Hoda, Gruber, Stephen B., From, Lynn, Busam, Klaus J., Hao, Honglin, Orlow, Irene, Kanetsky, Peter A., Luo, Li, Reiner, Anne S., Paine, Susan, Frank, Jill S., Bramson, Jennifer I., Marrett, Lorraine D., Gallagher, Richard P., Zanetti, Roberto, Rosso, Stefano, Dwyer, Terence, Cust, Anne E., Ollila, David W., Begg, Colin B., Berwick, Marianne, Conway, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486299/
https://ncbi.nlm.nih.gov/pubmed/26146664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.0493
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