Associations of MC1R genotype and patient phenotypes with BRAF and NRAS mutations in melanoma

Associations of MC1R with BRAF mutations in melanoma have been inconsistent between studies. We sought to determine for 1227 participants in the international population-based Genes, Environment and Melanoma (GEM) study whether MC1R and phenotypes were associated with melanoma BRAF/NRAS subtypes. We...

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Pubblicato in:J Invest Dermatol
Autori principali: Thomas, Nancy E., Edmiston, Sharon N., Kanetsky, Peter A., Busam, Klaus J., Kricker, Anne, Armstrong, Bruce K., Cust, Anne E., Anton-Culver, Hoda, Gruber, Stephen B., Luo, Li, Orlow, Irene, Reiner, Anne S., Gallagher, Richard P., Zanetti, Roberto, Rosso, Stefano, Sacchetto, Lidia, Dwyer, Terence, Parrish, Eloise A., Hao, Honglin, Gibbs, David C., Frank, Jill S., Ollila, David W., Begg, Colin B., Berwick, Marianne, Conway, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701875/
https://ncbi.nlm.nih.gov/pubmed/28842324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.07.832
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