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Clickable Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram

To date, the development of photoaffinity ligands targeting the human serotonin transporter (hSERT), a key protein involved in disease states such as depression and anxiety, have been radioisotope-based (i.e., (3)H or (125)I). This letter instead highlights three derivatives of the selective seroton...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem Lett
Prif Awduron: Yarravarapu, Nageswari, Geffert, Laura, Surratt, Christopher K., Cascio, Michael, Lapinsky, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200329/
https://ncbi.nlm.nih.gov/pubmed/30266542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.09.029
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