Novel Azido-Iodo Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram

[Image: see text] Three photoaffinity ligands (PALs) for the human serotonin transporter (hSERT) were synthesized based on the selective serotonin reuptake inhibitor (SSRI), (S)-citalopram (1). The classic 4-azido-3-iodo-phenyl group was appended to either the C-1 or C-5 position of the parent molec...

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Bibliografiske detaljer
Udgivet i:J Med Chem
Main Authors: Kumar, Vivek, Yarravarapu, Nageswari, Lapinsky, David J., Perley, Danielle, Felts, Bruce, Tomlinson, Michael J., Vaughan, Roxanne A., Henry, L. Keith, Lever, John R., Newman, Amy Hauck
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515784/
https://ncbi.nlm.nih.gov/pubmed/26153715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00682
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