A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone

Non-tropane-based photoaffinity ligands for the dopamine transporter (DAT) are relatively unexplored in contrast to tropane-based compounds such as cocaine. In order to fill this knowledge gap, a ligand was synthesized in which the aromatic ring of pyrovalerone was substituted with a photoreactive a...

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Hlavní autoři: Lapinsky, David J., Aggarwal, Shaili, Huang, Yurong, Surratt, Christopher K., Lever, John R., Foster, James D., Vaughan, Roxanne A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696686/
https://ncbi.nlm.nih.gov/pubmed/19442525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.04.057
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