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Impact of Multiple Single-Nucleotide Polymorphisms Within mprF on Daptomycin Resistance in Staphylococcus aureus

A number of single nucleotide polymorphisms (SNPs) within the mprF open reading frame (ORF) have been associated with daptomycin-resistance (DAP-R) in Staphylococcus aureus. Such SNPs have been found throughout the mprF ORF, although there are clearly preferred “hot spots” within this gene frequentl...

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Bibliographic Details
Published in:Microb Drug Resist
Main Authors: Yang, Soo-Jin, Mishra, Nagendra N., Kang, Kyoung-Mi, Lee, Gi-Yong, Park, Jong-Hwan, Bayer, Arnold S.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc., publishers 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200021/
https://ncbi.nlm.nih.gov/pubmed/29381428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mdr.2017.0156
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