Complement-mediated thrombotic microangiopathy as a link between endothelial damage and steroid-refractory GVHD

Transplant-associated thrombotic microangiopathy (TA-TMA), a complication of hematopoietic cell transplant (HCT), is associated with significant morbidity and mortality. The pathophysiology and overlap of TA-TMA with other posttransplant complications such as graft-versus-host disease (GVHD) is poor...

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Vydáno v:Blood Adv
Hlavní autoři: Wall, Sarah A., Zhao, Qiuhong, Yearsley, Martha, Blower, Luke, Agyeman, Akwasi, Ranganathan, Parvathi, Yang, Shangbin, Wu, Haiwa, Bostic, Matthew, Jaglowski, Samantha, Brammer, Jonathan E., William, Basem, Choe, Hannah, Mims, Alice S., Penza, Sam, Efebera, Yvonne, Devine, Steven, Cataland, Spero, Davies, Stella M., Vasu, Sumithira
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199668/
https://ncbi.nlm.nih.gov/pubmed/30327370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020321
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