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Atorvastatin for the Prophylaxis of Acute Graft vs. Host Disease (GVHD) in Patients Undergoing HLA-Matched Related Donor Hematopoietic Stem Cell Transplantation (HSCT)

Statins possess potent immunomodulatory effects that may play a role in preventing acute GVHD (aGVHD) following allogeneic hematopoietic cell transplantation (allo-HCT). We performed a Phase II study of atorvastatin for aGVHD prophylaxis when given to allo-HCT recipients and their HLA-matched siblin...

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Bibliographic Details
Published in:Biol Blood Marrow Transplant
Main Authors: Efebera, Yvonne A., Geyer, Susan, Andritsos, Leslie, Vasu, Sumithira, Jaglowski, Samantha, Bingman, Anissa, Blum, William, Klisovic, Rebecca, Hofmeister, Craig C., Benson, Don M., Penza, Sam, Elder, Patrick, Cortright, Katie, Kitzler, Rhonda, Coombes, Kevin, O’Donnell, Lynn, Daneault, Beth, Bradbury, Hillary, Zhang, Jianying, Chen, Xilin, Garman, Sabrina, Ranganathan, Parvathi, Yu, Xueyan, Hofstetter, Jessica, Yu, Jianhua, Garzon, Ramiro, Scrape, Scott R., Lozanski, Gerard, Devine, Steven M.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706501/
https://ncbi.nlm.nih.gov/pubmed/26256940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.07.034
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