Atorvastatin for the Prophylaxis of Acute Graft vs. Host Disease (GVHD) in Patients Undergoing HLA-Matched Related Donor Hematopoietic Stem Cell Transplantation (HSCT)

Statins possess potent immunomodulatory effects that may play a role in preventing acute GVHD (aGVHD) following allogeneic hematopoietic cell transplantation (allo-HCT). We performed a Phase II study of atorvastatin for aGVHD prophylaxis when given to allo-HCT recipients and their HLA-matched siblin...

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Pubblicato in:Biol Blood Marrow Transplant
Autori principali: Efebera, Yvonne A., Geyer, Susan, Andritsos, Leslie, Vasu, Sumithira, Jaglowski, Samantha, Bingman, Anissa, Blum, William, Klisovic, Rebecca, Hofmeister, Craig C., Benson, Don M., Penza, Sam, Elder, Patrick, Cortright, Katie, Kitzler, Rhonda, Coombes, Kevin, O’Donnell, Lynn, Daneault, Beth, Bradbury, Hillary, Zhang, Jianying, Chen, Xilin, Garman, Sabrina, Ranganathan, Parvathi, Yu, Xueyan, Hofstetter, Jessica, Yu, Jianhua, Garzon, Ramiro, Scrape, Scott R., Lozanski, Gerard, Devine, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706501/
https://ncbi.nlm.nih.gov/pubmed/26256940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.07.034
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