Comparison of Fixed Dose Reduced-Intensity Conditioning with Fludarabine and Busulfan to PK-guided Busulfan AUC (FluBu4K) in Hematopoietic Stem Cell Transplant for AML/MDS

A retrospective cohort study was conducted to assess differences in efficacy and tolerability between a busulfan AUC target of 16.4 mgxHr/L per day (FluBu4K) and a conventional RIC regimen (FluBu2). Adult patients with a diagnosis of AML or MDS who received fludarabine + busulfan conditioning with o...

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Detalhes bibliográficos
Publicado no:Leuk Lymphoma
Main Authors: Rasor, Brendan, Dickerson, Tyler, Zhao, Qiuhong, Elder, Patrick, Brammer, Jonathan E, Larkin, Karilyn, Jaglowski, Samantha, Mims, Alice, Penza, Sam, Vasu, Sumithira, Wall, Sarah A, William, Basem, Saad, Ayman, Roddy, Julianna V.F., Choe, Hannah, Puto, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012251/
https://ncbi.nlm.nih.gov/pubmed/33231122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2020.1849677
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