Sensing of red blood cells with decreased membrane deformability by the human spleen

The current paradigm in the pathogenesis of several hemolytic red blood cell disorders is that reduced cellular deformability is a key determinant of splenic sequestration of affected red cells. Three distinct features regulate cellular deformability: membrane deformability, surface area-to-volume r...

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Foilsithe in:Blood Adv
Main Authors: Safeukui, Innocent, Buffet, Pierre A., Deplaine, Guillaume, Perrot, Sylvie, Brousse, Valentine, Sauvanet, Alain, Aussilhou, Beatrice, Dokmak, Safi, Couvelard, Anne, Cazals-Hatem, Dominique, Mercereau-Puijalon, Odile, Milon, Geneviève, David, Peter H., Mohandas, Narla
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2018
Ábhair:
Red Cells, Iron, and Erythropoiesis
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199658/
https://ncbi.nlm.nih.gov/pubmed/30305267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018024562
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