The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro

Retention of poorly deformable red blood cells (RBCs) by the human spleen has been recognized as a critical determinant of pathogenesis in hereditary spherocytosis, malaria, and other RBC disorders. Using an ex vivo perfusion system, we had previously shown that retention of Plasmodium falciparum–in...

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Main Authors: Deplaine, Guillaume, Safeukui, Innocent, Jeddi, Fakhri, Lacoste, François, Brousse, Valentine, Perrot, Sylvie, Biligui, Sylvestre, Guillotte, Micheline, Guitton, Corinne, Dokmak, Safi, Aussilhou, Béatrice, Sauvanet, Alain, Cazals Hatem, Dominique, Paye, François, Thellier, Marc, Mazier, Dominique, Milon, Geneviève, Mohandas, Narla, Mercereau-Puijalon, Odile, David, Peter H., Buffet, Pierre A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Red Cells, Iron, and Erythropoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062417/
https://ncbi.nlm.nih.gov/pubmed/21163923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-312801
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