Sensing of red blood cells with decreased membrane deformability by the human spleen

The current paradigm in the pathogenesis of several hemolytic red blood cell disorders is that reduced cellular deformability is a key determinant of splenic sequestration of affected red cells. Three distinct features regulate cellular deformability: membrane deformability, surface area-to-volume r...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Safeukui, Innocent, Buffet, Pierre A., Deplaine, Guillaume, Perrot, Sylvie, Brousse, Valentine, Sauvanet, Alain, Aussilhou, Beatrice, Dokmak, Safi, Couvelard, Anne, Cazals-Hatem, Dominique, Mercereau-Puijalon, Odile, Milon, Geneviève, David, Peter H., Mohandas, Narla
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2018
Matèries:
Red Cells, Iron, and Erythropoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199658/
https://ncbi.nlm.nih.gov/pubmed/30305267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018024562
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