Sensing of red blood cells with decreased membrane deformability by the human spleen

The current paradigm in the pathogenesis of several hemolytic red blood cell disorders is that reduced cellular deformability is a key determinant of splenic sequestration of affected red cells. Three distinct features regulate cellular deformability: membrane deformability, surface area-to-volume r...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Safeukui, Innocent, Buffet, Pierre A., Deplaine, Guillaume, Perrot, Sylvie, Brousse, Valentine, Sauvanet, Alain, Aussilhou, Beatrice, Dokmak, Safi, Couvelard, Anne, Cazals-Hatem, Dominique, Mercereau-Puijalon, Odile, Milon, Geneviève, David, Peter H., Mohandas, Narla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199658/
https://ncbi.nlm.nih.gov/pubmed/30305267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018024562
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