Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis

Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target for renal inflammatory diseases, acting via Vascular Endothelial Growth Facto...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Marquez-Exposito, Laura, Lavoz, Carolina, Rodrigues-Diez, Raul R., Rayego-Mateos, Sandra, Orejudo, Macarena, Cantero-Navarro, Elena, Ortiz, Alberto, Egido, Jesús, Selgas, Rafael, Mezzano, Sergio, Ruiz-Ortega, Marta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199372/
https://ncbi.nlm.nih.gov/pubmed/30386246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01195
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