Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis

Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target for renal inflammatory diseases, acting via Vascular Endothelial Growth Facto...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Marquez-Exposito, Laura, Lavoz, Carolina, Rodrigues-Diez, Raul R., Rayego-Mateos, Sandra, Orejudo, Macarena, Cantero-Navarro, Elena, Ortiz, Alberto, Egido, Jesús, Selgas, Rafael, Mezzano, Sergio, Ruiz-Ortega, Marta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199372/
https://ncbi.nlm.nih.gov/pubmed/30386246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01195
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