DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity

The ability to perceive and respond to harmful conditions is crucial for the survival of any organism. The transcription factor DAF-16/FOXO is central to these responses, relaying distress signals into the expression of stress resistance and longevity promoting genes. However, its sufficiency in ful...

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Vydáno v:Nat Commun
Hlavní autoři: Lin, Xin-Xuan, Sen, Ilke, Janssens, Georges E., Zhou, Xin, Fonslow, Bryan R., Edgar, Daniel, Stroustrup, Nicholas, Swoboda, Peter, Yates, John R., Ruvkun, Gary, Riedel, Christian G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199276/
https://ncbi.nlm.nih.gov/pubmed/30353013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06624-0
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