Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules

The ability of transcriptional regulators to drive lineage conversion of somatic cells offers great potential for the treatment of human disease. To explore the concept of switching on specific target genes in heterologous cells, we developed a model system to screen candidate factors for their abil...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biotechnol Rep (Amst)
Päätekijät: Artuz, Crisbel M., Knights, Alexander J., Funnell, Alister P.W., Gonda, Thomas J., Ravid, Katya, Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197760/
https://ncbi.nlm.nih.gov/pubmed/30364711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2018.e00285
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