Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules

The ability of transcriptional regulators to drive lineage conversion of somatic cells offers great potential for the treatment of human disease. To explore the concept of switching on specific target genes in heterologous cells, we developed a model system to screen candidate factors for their abil...

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Bibliografische gegevens
Gepubliceerd in:Biotechnol Rep (Amst)
Hoofdauteurs: Artuz, Crisbel M., Knights, Alexander J., Funnell, Alister P.W., Gonda, Thomas J., Ravid, Katya, Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197760/
https://ncbi.nlm.nih.gov/pubmed/30364711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2018.e00285
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