Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7

Rabbits (Oryctolagus cuniculus) have been the very frequently used as animal models in the study of human lipid metabolism and atherosclerosis, because they have similar lipoprotein metabolism to humans. Most of hyperlipidemia and atherosclerosis rabbit models are produced by feeding rabbits a high-...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Lu, Rui, Yuan, Tingting, Wang, Yingge, Zhang, Ting, Yuan, Yuguo, Wu, Daijin, Zhou, Minya, He, Zhengyi, Lu, Yaoyao, Chen, Yajie, Fan, Jianglin, Liang, Jingyan, Cheng, Yong
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Research paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197696/
https://ncbi.nlm.nih.gov/pubmed/30243490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.020
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