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Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7

Rabbits (Oryctolagus cuniculus) have been the very frequently used as animal models in the study of human lipid metabolism and atherosclerosis, because they have similar lipoprotein metabolism to humans. Most of hyperlipidemia and atherosclerosis rabbit models are produced by feeding rabbits a high-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Lu, Rui, Yuan, Tingting, Wang, Yingge, Zhang, Ting, Yuan, Yuguo, Wu, Daijin, Zhou, Minya, He, Zhengyi, Lu, Yaoyao, Chen, Yajie, Fan, Jianglin, Liang, Jingyan, Cheng, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197696/
https://ncbi.nlm.nih.gov/pubmed/30243490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.020
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