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Targeted Disruption of LDLR Causes Hypercholesterolemia and Atherosclerosis in Yucatan Miniature Pigs

Recent progress in engineering the genomes of large animals has spurred increased interest in developing better animal models for diseases where current options are inadequate. Here, we report the creation of Yucatan miniature pigs with targeted disruptions of the low-density lipoprotein receptor (L...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Davis, Bryan T., Wang, Xiao-Jun, Rohret, Judy A., Struzynski, Jason T., Merricks, Elizabeth P., Bellinger, Dwight A., Rohret, Frank A., Nichols, Timothy C., Rogers, Christopher S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972179/
https://ncbi.nlm.nih.gov/pubmed/24691380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093457
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