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Effects of castration on atherosclerosis in Yucatan minipigs with genetic hypercholesterolemia

BACKGROUND: Low plasma testosterone, either spontaneous or as a result of androgen deprivation therapy for prostate cancer, is associated with an increased risk of cardiovascular events. The underlying mechanism in humans is not understood. Experimental studies in mice have shown that castration fac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shim, Jeong T., Schmidt, Nikolaj, Nogales, Paula, Larsen, Torben, Sørensen, Charlotte B., Bentzon, Jacob F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274396/
https://ncbi.nlm.nih.gov/pubmed/32502216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234131
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