Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosis

TNF-like weak inducer of apoptosis (TWEAK) and inhibition of protein synthesis with cycloheximide (CHX) sensitize for poly(I:C)-induced cell death. Notably, although CHX preferentially enhanced poly(I:C)-induced apoptosis, TWEAK enhanced primarily poly(I:C)-induced necroptosis. Both sensitizers of p...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Anany, Mohamed A., Kreckel, Jennifer, Füllsack, Simone, Rosenthal, Alevtina, Otto, Christoph, Siegmund, Daniela, Wajant, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197222/
https://ncbi.nlm.nih.gov/pubmed/30349023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1137-1
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