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Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling

We evaluated redundant and receptor-specific activities of TRADD, RIPK1, and FADD in RIPK3-expressing HeLa cells lacking expression of these proteins or any combination of two of these factors. We confirmed the opposing role of FADD in TNF- and TRAIL-induced necroptosis and observed an anti-necropto...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Füllsack, Simone, Rosenthal, Alevtina, Wajant, Harald, Siegmund, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370826/
https://ncbi.nlm.nih.gov/pubmed/30741924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1396-5
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