microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function

OBJECTIVES: Hepatic insulin resistance is a hallmark of type 2 diabetes and obesity. Insulin receptor signaling through AKT and FOXO has important metabolic effects that have traditionally been ascribed to regulation of gene expression. However, whether all the metabolic effects of FOXO arise from i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Langlet, Fanny, Tarbier, Marcel, Haeusler, Rebecca A., Camastra, Stefania, Ferrannini, Eleuterio, Friedländer, Marc R., Accili, Domenico
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197154/
https://ncbi.nlm.nih.gov/pubmed/30174230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.08.003
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