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Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids

Bile acids (BAs) exert pleiotropic metabolic effects, and physicochemical properties of different BAs affect their function. In rodents, insulin regulates BA composition, in part by regulating the BA 12α-hydroxylase CYP8B1. However, it is unclear whether a similar effect occurs in humans. To address...

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Bibliografiset tiedot
Päätekijät: Haeusler, Rebecca A., Astiarraga, Brenno, Camastra, Stefania, Accili, Domenico, Ferrannini, Ele
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Diabetes Association 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837033/
https://ncbi.nlm.nih.gov/pubmed/23884887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0639
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