Decreased expression of hepatic glucokinase in type 2 diabetes

BACKGROUND/OBJECTIVES: Increased endogenous glucose production is a hallmark of type 2 diabetes. Evidence from animal models has suggested that a likely cause of this is increased mRNA expression of glucose 6-phosphatase and phosphoenolpyruvate carboxykinase (encoded by G6PC, PCK1 and PCK2). But ano...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Haeusler, Rebecca A., Camastra, Stefania, Astiarraga, Brenno, Nannipieri, Monica, Anselmino, Marco, Ferrannini, Ele
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338311/
https://ncbi.nlm.nih.gov/pubmed/25737948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.12.007
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