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Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A

TMEM16A is a ligand-gated anion channel that is activated by intracellular Ca(2+). This channel comprises two independent pores and closely apposed Ca(2+) binding sites that are contained within each subunit of a homodimeric protein. Previously we characterized the influence of positively charged po...

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Vydáno v:eLife
Hlavní autoři: Lam, Andy KM, Dutzler, Raimund
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195346/
https://ncbi.nlm.nih.gov/pubmed/30311910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39122
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