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Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A

The TMEM16 proteins constitute a family of membrane proteins with unusual functional breadth, including lipid scramblases and Cl(−) channels. Members of both these branches are activated by Ca(2+), acting from the intracellular side, and probably share a common architecture, which was defined in the...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Lim, Novandy K., Lam, Andy K.M., Dutzler, Raimund
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089934/
https://ncbi.nlm.nih.gov/pubmed/27799318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611650
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