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The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization

Fertilization is fundamental for sexual reproduction, yet its molecular mechanisms are poorly understood. We found that an oocyte-expressed Ly6/uPAR protein, which we call Bouncer, is a crucial fertilization factor in zebrafish. Membrane-bound Bouncer mediates sperm-egg binding and is thus essential...

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Bibliografski detalji
Izdano u:Science
Glavni autori: Herberg, Sarah, Gert, Krista R., Schleiffer, Alexander, Pauli, Andrea
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195191/
https://ncbi.nlm.nih.gov/pubmed/30190407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat7113
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