Late-Onset Crohn’s Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics

BACKGROUND: Age of onset is linked to variations in clinical phenotypes and natural history in Crohn’s disease (CD). We aim to define etiologically more homogenous subgroups in CD based on ages of onset. METHODS: We examined the distribution of CD polygenetic risk score (PRS) across ages of diagnosi...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Li, Dalin, Haritunians, Talin, Landers, Carol, Potdar, Alka A, Yang, Shaohong, Huang, Hailiang, Schumm, L Philip, Daly, Mark, Targan, Stephan R, McGovern, Dermot P B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Clinical Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195175/
https://ncbi.nlm.nih.gov/pubmed/29860388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izy148
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