Late-Onset Crohn’s Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics

BACKGROUND: Age of onset is linked to variations in clinical phenotypes and natural history in Crohn’s disease (CD). We aim to define etiologically more homogenous subgroups in CD based on ages of onset. METHODS: We examined the distribution of CD polygenetic risk score (PRS) across ages of diagnosi...

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Dettagli Bibliografici
Pubblicato in:Inflamm Bowel Dis
Autori principali: Li, Dalin, Haritunians, Talin, Landers, Carol, Potdar, Alka A, Yang, Shaohong, Huang, Hailiang, Schumm, L Philip, Daly, Mark, Targan, Stephan R, McGovern, Dermot P B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Original Clinical Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195175/
https://ncbi.nlm.nih.gov/pubmed/29860388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izy148
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