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Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients
BACKGROUND: A novel prediction algorithm is needed for the identification of effective tumor associated mutated neoantigens. Only those with no homology to self wild type antigens are true predicted neoantigens (TPNAs) and can elicit an antitumor T cell response, not attenuated by central tolerance....
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6194606/ https://ncbi.nlm.nih.gov/pubmed/30340600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1662-9 |
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