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Prediction of individual immune responsiveness to a candidate vaccine by a systems vaccinology approach

BACKGROUND: We have previously shown that a candidate idiotype vaccine, based on the IGKV3-20 light chain protein, is able to induce activation of circulating antigen presenting cells (APCs) in both HCV-positive and HCV-negative subjects, with production of Th2-type cytokines. In addition, such a ca...

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Detalhes bibliográficos
Main Authors: Petrizzo, Annacarmen, Tagliamonte, Maria, Tornesello, Maria Lina, Buonaguro, Franco M, Buonaguro, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903560/
https://ncbi.nlm.nih.gov/pubmed/24428943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-11
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