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Increased β2‐adrenoceptor phosphorylation in airway smooth muscle in severe asthma: possible role of mast cell‐derived growth factors

The purpose of this study was to investigate whether growth factors produced by activated human lung mast cells (HLMCs) impair β(2)‐adrenoceptor (β(2)‐AR) function in human airway smooth muscle (ASM) cells. Protein array analysis confirmed the presence of various growth factors, including transformi...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Chachi, L., Alzahrani, A., Koziol‐White, C., Biddle, M., Bagadood, R., Panettieri, R. A., Bradding, P., Amrani, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194334/
https://ncbi.nlm.nih.gov/pubmed/30069878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13191
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