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Bidirectional counter-regulation of human lung mast cell and airway smooth muscle β(2)-adrenoceptors
Human lung mast cells (HLMCs) play a central role in asthma pathogenesis through their relocation to the airway smooth muscle (ASM) bundles. β(2) adrenoceptor (β(2)-AR)-agonists are used to relieve bronchoconstriction in asthma, but may reduce asthma control, particularly when used as monotherapy. W...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685750/ https://ncbi.nlm.nih.gov/pubmed/26608913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402232 |
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