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Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma
BACKGROUND: The mechanisms driving glucocorticoids (GC) insensitivity in patients with severe asthma are still unknown. Recent evidence suggests the existence of GC insensitive pathways in airway smooth muscle (ASM) caused by a defect in GC receptor (GRα) function. We examined whether other mechanis...
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| Publicado no: | Allergy |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154839/ https://ncbi.nlm.nih.gov/pubmed/27501780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13003 |
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