mRNAs and lncRNAs intrinsically form secondary structures with short end-to-end distances

The 5′ and 3′ termini of RNA play important roles in many cellular processes. Using Förster resonance energy transfer (FRET), we show that mRNAs and lncRNAs have an intrinsic propensity to fold in the absence of proteins into structures in which the 5′ end and 3′ end are ≤7 nm apart irrespective of...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Lai, Wan-Jung C., Kayedkhordeh, Mohammad, Cornell, Erica V., Farah, Elie, Bellaousov, Stanislav, Rietmeijer, Robert, Salsi, Enea, Mathews, David H., Ermolenko, Dmitri N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193969/
https://ncbi.nlm.nih.gov/pubmed/30337527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06792-z
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