Display of the HIV envelope protein at the yeast cell surface for immunogen development

As a step toward the development of variant forms of Env with enhanced immunogenic properties, we have expressed the glycoprotein in the yeast surface display system in a form that can be subjected to random mutagenesis followed by screening for forms with enhanced binding to germline antibodies. To...

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Publicat a:PLoS One
Autors principals: Mathew, Elizabeth, Zhu, Hong, Connelly, Sara M., Sullivan, Mark A., Brewer, Matthew G., Piepenbrink, Michael S., Kobie, James J., Dewhurst, Stephen, Dumont, Mark E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193675/
https://ncbi.nlm.nih.gov/pubmed/30335821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205756
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