The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

The Cancer/Testes (CT) Antigen HORMAD1 is germ cell-restricted and plays developmental roles in generation and processing of meiotic DNA Double Strand Breaks (DSB). Many tumors aberrantly overexpress HORMAD1 yet the potential impact of this CT antigen on cancer biology is unclear. We tested a potent...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Gao, Yanzhe, Kardos, Jordan, Yang, Yang, Tamir, Tigist Y., Mutter-Rottmayer, Elizabeth, Weissman, Bernard, Major, Michael B., Kim, William Y., Vaziri, Cyrus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192992/
https://ncbi.nlm.nih.gov/pubmed/30333500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33601-w
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