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Cancer cells activate damage-tolerant and error-prone DNA synthesis
Trans-lesion synthesis (TLS) is a DNA damage-tolerant and error-prone mode of DNA replication. Recent work shows that many cancer cells coopt an aberrantly expressed germ cell protein, melanoma antigen-A4 (MAGE-A4), to activate TLS. MAGE-A4–induced “pathological TLS” provides a potential mechanism t...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5160398/ https://ncbi.nlm.nih.gov/pubmed/28090576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1225547 |
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