Cancer cells activate damage-tolerant and error-prone DNA synthesis

Trans-lesion synthesis (TLS) is a DNA damage-tolerant and error-prone mode of DNA replication. Recent work shows that many cancer cells coopt an aberrantly expressed germ cell protein, melanoma antigen-A4 (MAGE-A4), to activate TLS. MAGE-A4–induced “pathological TLS” provides a potential mechanism t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Oncol
Päätekijät: Mutter-Rottmayer, Elizabeth, Gao, Yanzhe, Vaziri, Cyrus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Author's View
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160398/
https://ncbi.nlm.nih.gov/pubmed/28090576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1225547
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia